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Five secrets of high blood pressure treatment
Thirty percent of human population has a high blood pressure and everyone has a 90% risk to acquire it during the rest of the life. As a result, half of all human deaths are due to the major complications of high blood pressure, mainly stroke and heart attack.
Estimated risk is calculated by doctor. Taking the patient's age and blood pressure level, plus the presence of risk factors, such as smoking, diabetes, high cholesterol, obesity, atherosclerosis and renal dysfunction, doctor can say that the risk for the cardiovascular complications of high blood pressure during 5, 10 or 20 years will be certain amount of chances For example, smoking woman, aged below 65, with abdominal obesity (waist more than 102cm) and blood pressure 140-179/90-109 mm Hg will have 15-20% absolute risk of all cardiovascular events at 10 years. Just add one more risk factor (diabetes or high cholesterol) and the risk goes up to 30%. This is high risk and the treatment is definitely required. With people wanting to learn more about smoking cessation drugs, it has provided the necessary incentive for us to write this interesting article on smoking cessation drugs!
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Aerobic physical exercise of 30-40 min, daily or at least 3-4 days per week. More fruits, vegetables and potassium, and less sodium. Alcohol intake not more than 20-30 g of 'pure alcohol' per day (it corresponds to 150-200 ml of wine or a pint of beer). We have not actually resorted to roundabout means of getting our message on smoking cessation drugs through to you. All the matter here is genuine and to the point.
Reason three: negative side effects of antihypertensives are well known and include metabolic, lipid and hormonal disturbances including development of diabetes. We know that for the high risk patients (read - low life expectancy) the danger from the drug treatment is less than the benefit, but we do not know and we can not know without 20-30 years studies if it is the case for the low risk patients.
You should know how much effort is required to follow dietary restrictions or to stop smoking recommendations. Low compliance with these recommendations is usually accompanied by low compliance with drug therapy.
Be careful and distinguish absolute and relative risk reductions. Papers and pharmaceutical ads always present relative risk reduction which is more impressive. They even do not mention that it is 'relative'. That is because the absolute risk reduction could be as much as 2- 0%. Does not impress you, right? Let's take a clinical trial where 6% and 96% of patients had had fatal stroke in the treatment group and placebo group accordingly. Absolute risk reduction will be 96% - 60% = 36%, however relative risk reduction will be as much as ( 96% - 6%)/ 96% = 5%! Looks much better! Absolute risk reduction 36% means that from one thousand patients taking medication during 3-5 years, three or four could be saved from fatal stroke. Clinical trials don't say what will happen with those saved patients after 5 years. Presumably, the risk is postponed towards after 5 years period. Clinical trials also do not say which particular patients will be saved. It is like lottery, it could happen that 4 saved patients is just a difference between 44 saved and 40 preliminary died due to pharmaceutical side effects. Vioxx, Celebrex, Baycol are the known examples. It is the normal style of writers to add additional information with the intention of lengthening the length of an article. However, we have provided a short and concise article with only required information on smoking cessation drugs.
But people want more. People want the treatment that can effectively reverse the disease. The way to success here is in the proper coping with stresses. Stress causes activation of sympathetic system. Chronic activation of sympathetic system causes hypertension and obesity. Four out of six classes of antihypertensive drugs are designed to act upon sympathetic system. We were rather indecisive on where to stop in our writings of smoking cessation drugs. We just went on writing and writing to give a long article.
That is why official guidelines do not recommend starting drug treatment at the early stage of hypertension. Modern pharmaceutical treatment can not prevent or reverse the disease; it needs to be taken for life-long to maintain blood pressure at the recommended level. People are inclined to think that some matter found here that is pertaining to smoking cessation drugs is false. However, rest is assured, all that is written here is true!
2.The real benefit of the treatment is described by the absolute risk reduction which very often is not disclosed. 3.Side effects of the antihypertensive drugs during long-term consumption are common and serious.
Summary. Five secrets you should know about pharmaceutical and non-pharmaceutical treatment of the high blood pressure: 1.Pharmaceutical treatment should be initiated if estimated risk of cardiovascular complications is greater that 10% during 5 years or greater than 20% during 10 years.
What about non-pharmaceutical treatment? The treatment guidelines include the following non-pharmaceutical recommendations. 1.Stop smoking 2.Reduce body weight
As you see everyone has to pay for this risk reduction not only by inconvenience and cost of pharmaceuticals, but also by the risk of unpleasant or life-threatening side effects. For the patients with high estimated risk (more than 10% during 5 years or more than 20% during 10 years) this price is considered to be a worth-while to pay. The value of this composition is achieved if after reading it, your knowledge on smoking cessation drugs is greatly influenced. This is how we find out that the meaning of smoking cessation drugs has really entered you!
Reason two: even if we decide to operate the relative instead of absolute risk reduction, we CAN NOT do this, because available clinical trials have demonstrated risk reduction for the high risk patients and we can not extrapolate these results to the low risk patients. Clinical trials on low risk patients were not performed and we do not know if the harm of the treatment overbalances the benefit. The initial stages of this article on smoking cessation drugs proved to be difficult. However, with hard work and perseverance, we have succeeded in providing an interesting and informative article for you to read.
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Can we manage stress and accompanied sympathetic activation without drugs? The task is not easy. You may say that effective stress reduction is only possible after radical change of working or family environment. I may add that even after that, the man will be caught by the new stress. The problem is in people's attitude and the ability to cope with stress and to avoid chronic anger. Those who are able, live more than hundred years. The researches on centenarians have demonstrated their unique ability to avoid damaging reactions on the stressful situations. As we got to writing on smoking cessation drugs, we found that the time we were given to write was inadequate to write all that there is to write about smoking cessation drugs! So vast are its resources.
For people who want to be healthy and prevent or at least control this dangerous disease, there is a good news. Non-pharmaceutical recommendations really work; you will definitely reduce your risk by following them.
6.Reduce stress These non-pharmaceutical approaches have a proven efficacy in the reduction and prevention of high blood pressure. But they require substantial perseverance and will-power to comply with.
4.Non-pharmaceutical treatments of hypertension really work. Although they require much more effort and will-power to implement in compare with daily chemical drugs consumption, they will protect you not only against hypertension, but also against the high cholesterol, diabetes, cancer, obesity and other diseases. Plus you will get better and healthier life, with much more energy and satisfaction. You may be inquisitive as to where we got the matter for writing this article on smoking cessation drugs. Of course through our general knowledge, and the Internet!
5.We must learn from centenarians how to escape diseases. Centenarians have innate ability to cope with stress; they are natural stress-shedders. They are not preoccupied with worry, hostility and anxiety. They avoid unhealthy thinking, like anger, sadness, guilt and fear. It is possible to develop such personality with modern stress-management and personal development techniques. Inspiration can be considered to be one of the key ingredients to writing. Only if one is inspired, can one get to writing on any subject especially like smoking cessation drugs.
Is it a great success? Unfortunately not. Pharmaceutical treatment can not reverse the disease. The patient with developed arterial hypertension can only hope to reduce the risk of high blood pressure complications. How big is this risk reduction? Relative risk reduction is less than 25% during 2-5 years for all major cardiovascular complications. It is higher for stroke (36-45%) and less for heart attacks (10-15%). When all risks are combined, the relative risk reduction is close to 25%. We have omitted irrelevant information from this composition on smoking cessation drugs as we though that unnecessary information may make the reader bored of reading the composition.
For the patients with initial stages of hypertension and low risk the balance between benefits and drawbacks of antihypertensive drugs is not established. There are three reasons for being reluctant to start taking antihypertensive drugs without having 10% estimated risk of cardiovascular complications. The more interesting an article, the more takers there are for the article. So we have made it a point to make this article on smoking cessation drugs as interesting as possible!
About the author: Dr. Alexander Alfimov M.D, Ph.D. has graduated from St. Petersburg Medical Academy in 1987. He has been working for eleven years as a head of clinical research department of the big pharmaceutical company, producing and marketing six antihypertensive drugs. We take pride in saying that this article on smoking cessation drugs is like a jewel of our articles. This article has been accepted by the general public as a most informative article on smoking cessation drugs.
Medical scientists are fighting this life-threatening disease and they have gained some success. That is the development of several classes of antihypertensive drugs and definition of 'normal' levels of blood pressure that should be maintained to reduce the risk of cardiovascular complications and death. Having been given the assignment of writing an interesting presentation on smoking cessation drugs, this is what we came up with. Just hope you find it interesting too!
To select most effective stress-management technique for yourself, I recommend you to try first those, having proven blood pressure reducing effect, like yoga, meditation and computerized devices reducing respiration rate. Coping with stress is the obvious way to escape from Number One Killer and to live the full life span we are designed for. It is not necessary that only the learned can write about smoking cessation drugs. As long as one ahs a flair for writing, and an interest for gaining information on smoking cessation drugs, anyone can write about it.
www.slowbreath.com
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